Why lipostatic set point systems are unlikely to evolve

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Why lipostatic set point systems are unlikely to evolve

OBJECTIVES Body fatness is widely assumed to be regulated by a lipostatic set-point system, which has evolved in response to trade-offs in the risks of mortality. Increasing fatness makes the risk of starvation lower but increases the risk of predation. Yet other models are available. The aim of this work is to evaluate using mathematical modeling whether set-point systems are more likely to ev...

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ژورنال

عنوان ژورنال: Molecular Metabolism

سال: 2018

ISSN: 2212-8778

DOI: 10.1016/j.molmet.2017.10.007